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REVIEW ARTICLE
Year : 2008  |  Volume : 3  |  Issue : 1  |  Page : 13-20

Gastrointestinal involvement in systemic sclerosis


Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA

Correspondence Address:
D Khanna
Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA
USA
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Source of Support: None, Conflict of Interest: None


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Disease of the gastrointestinal tract (GIT) occurs in approximately 90% of patients with scleroderma (systemic sclero- sis) and has a major impact on their quality of life. Every part of the GIT can be involved in scleroderma and may include the mouth (xerostomia), esophagus (dysmotility, acid reflux), stomach (vascular ectasia, gastroparesis), intestines (vascular lesions, hypomotility, bacterial overgrowth, intestinal pseudo-obstruction) and anorectal system (fecal incontinence). This review provides practical guidance in the diagnosis and treatment of systemic sclerosis- associated GIT involvement.


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