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REVIEW ARTICLE
Year : 2010  |  Volume : 5  |  Issue : 2  |  Page : 69-75

Diagnosis and management of systemic sclerosis


UCLA Scleroderma Program, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

Correspondence Address:
Dinesh Khanna
UCLA Scleroderma Program, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

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Source of Support: None, Conflict of Interest: None


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Systemic sclerosis (Scleroderma, SSc) is associated with major mortality and morbidity that arises from the devel- opment of specific complications of the disease, including organ-based complications. The frequency and diverse nature of these complications makes systematic assessment and long-term follow-up essential to good manage- ment of SSc. This review will discuss the natural history of SSc, the predictors of progressive skin and internal organ involvement and current therapeutic management of these complications.


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