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REVIEW ARTICLE
Year : 2015  |  Volume : 10  |  Issue : 5  |  Page : 84-94

Behçet's disease: Review of management


Institute of Ageing and Chronic Disease, University of Liverpool and National Behçet's Syndrome Centre of Excellence, Aintree University Hospital, Liverpool, UK

Correspondence Address:
Robert J Moots
Institute of Ageing and Chronic Disease, University of Liverpool and National Behçet's Syndrome Centre of Excellence, Aintree University Hospital, Liverpool, UK

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Source of Support: None, Conflict of Interest: None


DOI: 10.1016/j.injr.2015.09.003

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Introduction: Behçet's disease (BD) is a chronic relapsing and remitting vasculitis of unknown aetiology, which has the potential to affect almost all body systems due to its capacity to involve both arterial and venous sides of the vascular system and results in significant organ-specific morbidity and mortality. Whilst occurring worldwide, the prevalence is highest along the traditional 'silk road'. The pathological processes underlying BD remain poorly understood and the evidence base to inform optimal management is limited. Aim: To briefly discuss clinical features of BD and, through analysis of the current literature, provide a concise review of the currently available treatment modalities available. Opinion: There is a paucity of randomised controlled trials and robust clinical studies to guide treatment on various manifestations of BD. We have attempted to provide a system- wise step-up treatment guidance for BD. The current evidence base for BD management is based on limited high quality studies, clinical trials and various expert committee opinions.


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