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ORIGINAL ARTICLE
Year : 2016  |  Volume : 11  |  Issue : 1  |  Page : 26-31

Comparative study of DAS 28 ESR and DAS 28 CRP among rheumatoid arthritis patients in India


1 Child In Need Institute, Kolkata, India
2 Department of Medicine and Rheumatology, Medical College and Hospital, Kolkata, India

Correspondence Address:
Rathindra Nath Sarkar
Department of Medicine and Rheumatology, Medical College and Hospital, Kolkata
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.1016/j.injr.2015.10.006

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Background: The Disease Activity Score (DAS) in rheumatoid arthritis (RA) involving 28 joints and using erythrocyte stimulation rate (ESR) is used frequently. But the inability of DAS 28 ESR to reflect short-term changes in disease activity has given rise to DAS 28 using C- reactive protein (CRP). The objective of the present study was to compare DAS 28 CRP with DAS 28 ESR. Methods: 294 patients of RA diagnosed as per ACR EULAR 2010 revised classification criteria for RA were included. New cutoff values of remission, low, moderate and high disease activity using DAS 28 CRP were defined. Result: There was a good correlation between DAS 28 ESR and DAS 28 CRP. On classifying the disease activity of the subjects according to new cutoff values of DAS 28 CRP, there was substantial agreement with classification according to DAS 28 ESR. Conclusion: DAS 28 CRP may be considered as an alternative to DAS 28 ESR.


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