Tab Application Banner
  • Users Online: 1101
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2019  |  Volume : 14  |  Issue : 1  |  Page : 65-68

Childhood polyarteritis nodosa presenting as central nervous system vasculitis

1 Consultant Rheumatologist, Gleneagles Global Health City, Chennai, Tamil Nadu, India
2 Consultant Paediatrician, Gleneagles Global Health City, Chennai, Tamil Nadu, India
3 Consultant Pathologist, Gleneagles Global Health City, Chennai, Tamil Nadu, India
4 Consultant Radiologist, Gleneagles Global Health City, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Sham Santhanam
No: 16 A, Pallavan Salai, Nesapakkam, KK Nagar West, Chennai - 600 078, Tamil Nadu
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/injr.injr_129_18

Rights and Permissions

Childhood polyarteritis nodosa (c-PAN) is one of the rare causes of childhood central nervous system (CNS) vasculitis. Nervous system involvement is less common, with peripheral nervous system frequently involved than the CNS. To the best of our knowledge, a very few cases of c-PAN presenting as CNS vasculitis involving both the anterior and posterior circulation have been reported in the literature. Hence, we report a 14-year-old female presenting with extensive CNS vasculitis with severe neurological deficits. She also had systemic symptoms, myalgia, leg ulcers, weight loss, axonal neuropathy, and proteinuria. She was treated with pulse methylprednisolone, monthly intravenous pulse cyclophosphamide, and intravenous immunoglobulin. At the end of 3 months, her proteinuria came down significantly with no major improvement in her neurological status. Hence, c-PAN has to be considered in the differential diagnosis of childhood CNS vasculitis and if not picked up early can lead to severe neurological deficits.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded92    
    Comments [Add]    
    Cited by others 1    

Recommend this journal