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Rheumatoid arthritis disease activity index-5: Utility in busy clinical settings

1 Department of Medicine, PGIMS, Rohtak, Haryana, India
2 Department of Medicine, SHKM Government Medical College, Nalhar, Haryana, India

Date of Web Publication27-Jan-2017

Correspondence Address:
Vikram Singh Tanwar,
Department of Medicine, SHKM Government Medical College, Nalhar - 122 107, Haryana
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Source of Support: None, Conflict of Interest: None


Objective: To assess disease activity using Rheumatoid Arthritis Disease Activity Index-5 (RADAI-5) in patients with rheumatoid arthritis (RA) and its correlation with Disease Activity Score using 28 joint count (DAS28) and Clinical Disease Activity Index (CDAI).
Methods: One hundred patients with active RA (as per ACR 1987 criteria) were assessed for disease activity using DAS28, CDAI, and RADAI-5. Spearman's correlation coefficient (ρ) and Cronbach's alpha were measured to assess the correlation between different disease activity scores and internal consistency, respectively.
Results: In the study population, 81 patients were women and 19 patients were men. Mean age of the patients was 44.4 (±11.8) years. The median scores (interquartile range) for DAS28, CDAI, and RADAI-5 were 5.6 (2.0), 26.5 (22.0), and 5.8 (3.2), respectively. RADAI-5 was found to be significantly correlated with DAS28 and CDAI (all P< 0.001). Cronbach's alpha was highest for the RADAI-5.
Conclusion: RADAI-5 had a positive correlation to DAS28 and CDAI for the assessment of disease activity, and it may be a good alternative to DAS28 and CDAI in busy outdoor settings.

Keywords: Clinical Disease Activity Index, Disease Activity Score, disease activity

How to cite this URL:
Singh H, Tanwar VS, Sukhija G, Mathur R, Kaur P. Rheumatoid arthritis disease activity index-5: Utility in busy clinical settings. Indian J Rheumatol [Epub ahead of print] [cited 2017 May 25]. Available from: http://www.indianjrheumatol.com/preprintarticle.asp?id=199127



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