Indian Journal of Rheumatology

REVIEW ARTICLE
Year
: 2012  |  Volume : 7  |  Issue : 5  |  Page : 80--86

Juvenile dermatomyositis: A review of clinical features and management


S Habibi1, AV Ramanan2 
1 Department of Rheumatology, Nizam's Institute of Medical Sciences, Hyderabad, India
2 Department of Paediatric Rheumatology, Bristol Royal Hospital for Children and Royal National Hospital for Rheumatic Diseases, UK

Correspondence Address:
S Habibi
Department of Rheumatology, Nizam«SQ»s Institute of Medical Sciences, Hyderabad, India

Juvenile dermatomyositis is the most common of the idiopathic inflammatory myositis of childhood. It is characterised by a pathognomic skin rash along with proximal muscle weakness. It may also affect organs other than the muscle and skin. Calcinosis and lipodystrophy are complications of long-standing untreated or poorly treated disease, asso- ciated with chronic morbidity. A variety of environmental and genetic risk factors are implicated in its pathogenesis. Up-regulation of genes by type-I interferon appears central. Corticosteroids along with methotrexate are the mainstay of therapy. Disease outcome is in general good.


How to cite this article:
Habibi S, Ramanan A V. Juvenile dermatomyositis: A review of clinical features and management .Indian J Rheumatol 2012;7:80-86


How to cite this URL:
Habibi S, Ramanan A V. Juvenile dermatomyositis: A review of clinical features and management . Indian J Rheumatol [serial online] 2012 [cited 2020 Jul 10 ];7:80-86
Available from: http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2012;volume=7;issue=5;spage=80;epage=86;aulast=Habibi;type=0