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  Access statistics : Table of Contents
   2014| June  | Volume 9 | Issue 2  
    Online since July 11, 2016

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Demystifying statistics: How to choose a statistical test?
Subramanian Shankar, Ramakant Singh
June 2014, 9(2):77-81
The young researcher today is confronted with a choice of hundreds of statistical tests, both while reading research works or while planning own research. The principles guiding the choice of statistical tests are simple and this article, aimed at the young researcher, aims to demystify the same.
[ABSTRACT]   Full text not available  [PDF]  [Mobile Full text]  [EPub]
  505 83 -
Nocardia infection in SLE: A case series of three patients
BN Prasad, Ramnath Misra, Vikas Agarwal, Able Lawrence, Amita Aggarwal
June 2014, 9(2):53-56
Objectives: Nocardia infections have been described in immunosuppressed patient including patients with systemic lupus erythematosus (SLE). There are only a few case series in patients with SLE. Thus we studied the clinical presentations, organ involvement, treatment and outcome of cases of nocardial infection in the SLE patients. Methods: Records of SLE patients who attended our rheumatology clinic in the last 25 years were reviewed and cases of nocardial infection were identified and data was collected from case records. Results: Three cases of nocardiosis were found in our lupus series, giving a prevalence of 0.2%. Brain involvement was seen in all 3, whereas pulmonary and subcutaneous abscess was found in two patients each. All patients were managed with antibiotics and one pa- tient required surgical drainage. All recovered without any morbidity. Conclusion: Nocardial infection, though rare in SLE has a good outcome. Involvement of brain, skin and lung together in a patient with background of immunosuppression should raise a suspicion of nocardial infection.
[ABSTRACT]   Full text not available  [PDF]  [Mobile Full text]  [EPub]
  506 61 -
Immunosenescence in rheumatoid arthritis: Use of CD28 negative T cells to predict treatment response
Subir Roy
June 2014, 9(2):62-68
Not many years ago achieving remission in rheumatoid arthritis (RA) was difficult due to lack of effective treatment. With the advent of biologics, remission is very much within reach. But biologics are expensive. And not all patients respond adequately to biologics. Hence it will be useful if we have a marker which predicts response to any disease modifying anti-rheumatic drug (DMARD), whether conventional or biologic. Expansion of CD28-ve T cells is characteristically seen in RA. Both CD28-ve T Cells and RA are believed to be linked to immunosenescence. The available evidence is suggestive of an intimate relationship between RA and clonal expansion of CD28-ve T cells. Newer biomarkers are constantly being looked at and CD28-ve T cells is one of them. In this review the rela- tionship between immune disorders like RA and immunosenescence and significance of CD28-ve T cells in RA is discussed.
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  496 68 -
Clinical assessment and health status in standard care in Indian and Iranian patients suffering from rheumatoid arthritis (RA)
Hadi Yousefi, Arvind Chopra, Reza Farrokhseresht, Sanjeev Sarmukaddam
June 2014, 9(2):57-61
Disease activity and quality of life (QOL) including functional status in rheumatoid arthritis (RA) is influenced by several ethnic, cultural and other factors. Standard of care manage- ment should cater for country specific needs. Objectives: To assess and compare clinical disease characteristics and health status in pa- tients with RA from two countries, India and Iran. Material and methods: A cross-sectional survey of 140 RA patients (Indian70 and Iranian70) was chosen from rheumatology outpatients (Bandar Abbas, Iran and Pune, India) in random manner. One of the authors evaluated all patients under Rheumatologist super- vision. Standard evaluation was as per current American College of Rheumatology guide- lines and included a 68/66 joint count and laboratory tests. Health assessment questionnaire (CRD Pune version HAQ) and SF36v2 was utilized to assess functional and health status. While Iranian patients were all Muslims, the Indian patients were pre- dominantly Hindu. Results: The groups matched well for age, gender, duration of disease and rheumatoid factor. Patients in Iran had less years of education as compared to patients from India (p < 0.001), Pains and SF 36 domains (barring vitality, social function and mental health) and sedimentation rate (ESR) scored significantly higher in the Iranian group. Swollen joint counts, global disease assessment and blood hemoglobin were higher in the Indian group. The overall DAS 28 (disease activity score) index, general health (VAS), HAQ and SF 36 Mental health domain scores did not differ significantly in two groups. Conclusions: Though there were some important differences in pain perception, joint counts and QOL, the study cohorts of RA belonging to the Iranian and Indian ethnicity were similar for disease activity (DAS) and functional status (HAQ).
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  456 57 -
Rheumatology quiz
Vivek Aryaa, Varun Dhir
June 2014, 9(2):73-73
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  353 126 -
Rheumatology in undergraduate curriculum
Bidyut Das
June 2014, 9(2):69-72
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  391 65 -
Unity in diversity: Rheumatoid arthritis across countries
Sapan Pandya, Parasar Ghosh
June 2014, 9(2):51-52
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  361 69 -
International publications of interest from India (December 2013-February 2014)
Vivek Arya
June 2014, 9(2):74-76
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  351 67 -
Prolonged remission of rheumatoid arthritis with dexamethasone cyclophosphamide pulse therapy: A case series
Ramji Gupta, Sarthak Gupta
June 2014, 9(2):98-100
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  311 76 -
Purpura of all four limbs with gangrene in a child with Juvenile Idiopathic Arthritis
Bijay Kumar Meher, Sivaraj Pradeep, Deepti Damayanty Pradhan, Kaushik Parasar Patra, Niranjan Mohanty
June 2014, 9(2):82-83
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  330 45 -
Forestier disease
S Sham, S Rajeswari, TN Tamilselvam, M Madheshwaran
June 2014, 9(2):86-87
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  314 41 -
Pellegrini-Stieda's lesion in female patient without any history of trauma
Anjana Pandey, Sudhanshu Pandey, Mridul Chaturvedi, Sunil Kumar
June 2014, 9(2):101-102
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  276 45 -
Elderly lady with ischemic heart disease and rash
Anjali G Rajadhyaksha, Chakor S Vora, Juhi Kawale, Riya Balikar, Archana S Sonawale
June 2014, 9(2):84-85
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  274 32 -
Rheumatology reviews: April-June 2014
Sukhbir Uppal
June 2014, 9(2):88-95
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  275 30 -
Special report: APLAR 2014
Anuj N Shukla
June 2014, 9(2):103-104
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  267 31 -
Hypoparathyroidism - A rare endocrinological abnormality in systemic lupus erythematosus
Kavitha Mohanasundaram, Hema Shankar, Tiruchengode Natesan Tamilselvam, Sankaralingam Rajeswari
June 2014, 9(2):96-97
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  237 34 -