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  Indian J Med Microbiol
 

Figure 1: mRNA gene expression of P-glycoprotein. The first bar represents the P-glycoprotein expression of all the patients at baseline. The second bar represents the P-glycoprotein expression in PBMCs of patients who responded with 6 weeks of steroid therapy. The third bar represents the P-glycoprotein expression in PBMCs of patients who did not respond after 6 weeks of steroid therapy. Peripheral blood mononuclear cells were isolated at baseline, during remission and resistant, and the mRNA levels of P-glycoprotein were quantified by real-time polymerase chain reaction technique. The experiments are representative of three independent series. Pooled data of all the experiments are represented as mean ± standard error of the mean. Significant differences compared to control were indicated by P<0.05

Figure 1: mRNA gene expression of P-glycoprotein. The   first bar represents the P-glycoprotein expression of all the patients at baseline. The second bar represents the P-glycoprotein expression in PBMCs of patients who responded with 6 weeks of steroid therapy. The third bar represents the P-glycoprotein expression in PBMCs of patients who did not respond after 6 weeks of steroid therapy. Peripheral blood mononuclear cells were isolated at baseline, during remission and resistant, and the mRNA levels of P-glycoprotein were quantified by real-time polymerase chain reaction technique. The experiments are representative of three independent series. Pooled data of all the experiments are represented as mean ± standard error of the mean. Significant differences compared to control were indicated by <i>P</i><0.05