Close
  Indian J Med Microbiol
 

Figure 2: (a) Canonical TGF β signaling, (b) Non canonical TGF β signaling pathway. TGFβ: Transforming Growth Factor - β, TGFβRI and II: TGF β Receptor Subunits I and II, pSmads (3,4,5): Phosphorylated Smad Adaptor Proteins, TAK1: Transforming growth factor-β activated kinase 1, JNK: c-Jun N-terminal kinases, TRAF: TNF (Tumor Necrosis Factor) Receptor Associated Protein, p38: Negative Regulator of Ras, MAP-K: Mitogen-activated Protein Kinase, Erk1: Extracellular signal Regulated Kinase 1, RhoA: Small GTPase protein of Rho family, ROCK: Rho-associated protein kinase, Jun and Fos: c-Jun and c-Fos forms the AP-1 early response transcription factor

Figure 2: (a) Canonical TGF β signaling, (b) Non canonical TGF β signaling pathway. TGFβ: Transforming Growth Factor - β, TGFβRI and II: TGF β Receptor Subunits I and II, pSmads (3,4,5): Phosphorylated Smad Adaptor Proteins, TAK1: Transforming growth factor-β activated kinase 1, JNK: c-Jun N-terminal kinases, TRAF: TNF (Tumor Necrosis Factor) Receptor Associated Protein, p38: Negative Regulator of Ras, MAP-K: Mitogen-activated Protein Kinase, Erk1: Extracellular signal Regulated Kinase 1, RhoA: Small GTPase protein of Rho family, ROCK: Rho-associated protein kinase, Jun and Fos: c-Jun and c-Fos forms the AP-1 early response transcription factor