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  Indian J Med Microbiol
 

Figure 1: Levels of CXCL6, CCL2, CCL8, CCL15, RANTES, IL6, VEGF, and OA FLS cell stimulation as-says (a-h). Cells were either left unstimulated (negative control) or stimulated with synovial fluid MP, MP free synovial fluid (2.5 μl), IL-1β (125 pg/well) (thermoflished scientific, USA) (positive control), and lipopolysaccharides from Escherichia coli) O26;B6 [LPS (1 μg/well) (sigma asdrice, USA) positive control] for 24 h. The data are expressed as mean ± standard deviation of three independent experiments (n = 0). The variation between two independent groups was statistically assessed by unpaired t-test with Wekh's correction. Horizontal lined indicates standard deviation, CXCL, (C-X-C) motif ligand; CCL, (C-C) motif ligand; IL6: Interleukin-6, RANTES: Regulated on activation, normal T-cell expressed and secreted, VEGF: Vascular endothelial grouth factor, BAFF: B-cell activating factor, NV: Negative control (Unstimulated cells), MP: Microparticle, SF: Synovial fluid, LPS: Lipopolysaccharides, RA FLS: Rheumatoid arthritis fibroblast-like synoviocytes, OA FLS: Osteoarthritis fibroblast-like synoviocytes, *P < 0.05, **P < 0.01, ***P < 0.001

Figure 1: Levels of CXCL6, CCL2, CCL8, CCL15, RANTES, IL6, VEGF, and OA FLS cell stimulation as-says (a-h). Cells were either left unstimulated (negative control) or stimulated with synovial fluid MP, MP free synovial fluid (2.5 μl), IL-1β (125 pg/well) (thermoflished scientific, USA) (positive control), and lipopolysaccharides from <i>Escherichia coli</i>) O26;B6 [LPS (1 μg/well) (sigma asdrice, USA) positive control] for 24 h. The data are expressed as mean ± standard deviation of three independent experiments (<i>n</i> = 0). The variation between two independent groups was statistically assessed by unpaired t-test with Wekh's correction. Horizontal lined indicates standard deviation, CXCL, (C-X-C) motif ligand; CCL, (C-C) motif ligand; IL6: Interleukin-6, RANTES: Regulated on activation, normal T-cell expressed and secreted, VEGF: Vascular endothelial grouth factor, BAFF: B-cell activating factor, NV: Negative control (Unstimulated cells), MP: Microparticle, SF: Synovial fluid, LPS: Lipopolysaccharides, RA FLS: Rheumatoid arthritis fibroblast-like synoviocytes, OA FLS: Osteoarthritis fibroblast-like synoviocytes, *<i>P</i> < 0.05, **<i>P</i> < 0.01, ***<i>P</i> < 0.001