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  Indian J Med Microbiol
 

Figure 1: Serum metabolomics (a) three dimensional score plot obtained from PCA analysis of 1D 1H CPMG NMR based serum metabolic profiles showing clustering and separation between healthy control and inflammatory myositis patients (b) two dimensional score plot after PCA analysis of sera from myositis patients with active and inactive disease (c) screening of metabolites responsible form the group separation in the score plot identified based on variable importance in projection score > 2.0 (d) variable importance in projection projection suggesting elevated phenylalanine-to-tyrosine ratio (PTR) and glutamate to glutamine ration (EQR) (e) variable importance in projection projection suggesting elevated significantly decreased in the sera of active myositis patients (f) representative ROC curves of discriminatory metabolites

Figure 1: Serum metabolomics (a) three dimensional score plot obtained from PCA analysis of 1D 1H CPMG NMR based serum metabolic profiles showing clustering and separation between healthy control and inflammatory myositis patients (b) two dimensional score plot after PCA analysis of sera from myositis patients with active and inactive disease (c) screening of metabolites responsible form the group separation in the score plot identified based on variable importance in projection score > 2.0 (d) variable importance in projection projection suggesting elevated phenylalanine-to-tyrosine ratio (PTR) and glutamate to glutamine ration (EQR) (e) variable importance in projection projection suggesting elevated significantly decreased in the sera of active myositis patients (f) representative ROC curves of discriminatory metabolites