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Year : 2006  |  Volume : 1  |  Issue : 1  |  Page : 3-7

Effects of ginger on primary knee osteoarthritis

1 Hormozgan University of Medical Sciences and Health Services, Bandar Abbas, Iran
2 Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran

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Source of Support: None, Conflict of Interest: None

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Introduction: Nonsteroidal anti-inflammatory drugs are effective in relieving osteoarthritis pain, but because of their side effects, search continues for agents that might provide improvement in symptoms with minimal addition- al risk. Evidence from previous studies suggests that ginger can reduce osteoarthritis pain. The aim of this study is to compare the effects of indomethacin and ginger on relieving osteoarthritis pain. Materials and Methods: A double blind, parallel group clinical trial was designed to evaluate the response of 52 patients with knee osteoarthritis to ginger and indomethacin. Results: Analysis of the mean for pain on standing (based on 100 mm visual analogue scale) showed improve- ment in both groups (22.5 mm in indomethacin group and 23 mm in ginger group, P value = 0.1). Results of improvement in pain after walking 50 feet were similar in both groups (23.5 mm in indomethacin group and 21.4 mm in ginger group, P value = 0.34). Changes in total Western Ontario and MacMaster Universities Osteoarthritis Index score were significant in both groups (4.62 in indomethacin group and 3.39 in ginger group, P value = 0.65). Conclusion: Ginger is as effective as indomethacin in relieving symptoms of osteoarthritis with negligible side effects. Therefore in patients with intolerance to indomethacin, ginger may be substituted.

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