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REVIEW ARTICLE
Year : 2020  |  Volume : 15  |  Issue : 6  |  Page : 112-122

Juvenile dermatomyositis: Controversies and recent developments in management


1 Advanced Pediatrics Centre, Allergy Immunology Unit, Postgraduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Pediatrics and Chief, Advanced Pediatrics Center, Allergy Immunology Unit, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Dr. Surjit Singh
Department of Pediatrics and Chief, Advanced Pediatrics Center, Allergy Immunology Unit, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/injr.injr_107_20

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Juvenile dermatomyositis (JDM) is an autoimmune disorder of childhood that mainly affects the skin and muscles. As compared to adults, children are more likely to suffer from disease relapses and long-term complications such as lipodystrophy, insulin resistance, calcinosis, and systemic vasculopathy. There have been significant advancements in our understanding of the pathophysiology, disease course and complications of JDM in the last two decades. Due to scarcity of clinical trials in JDM, therapeutic decisions in every patient with JDM remain a challenge. This review aims to provide a comprehensive overview of the controversies, challenges in clinical management and latest advances in treatment regimens of JDM.


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