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Sporadic inclusion body myositis in the rheumatology clinic


 Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, SP, Brazil (BR), Brazil

Correspondence Address:
Samuel Katsuyuki Shinjo,
Division of Rheumatology, Laboratório de Miopatias Inflamatórias, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, SP
Brazil
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/injr.injr_80_20

Sporadic inclusion body myositis (sIBM) is a progressive and insidious skeletal muscle disorder characterized classically by the quadriceps, wrist, and finger flexor weakness. The main irreversible complications of sIBM are dysphagia and walking difficulties. The disease affects more men than women, and the symptom onset mainly occurs between 50 and 70 years of age. Due to its slow progression, sIBM diagnosis is frequently delayed and therefore misdiagnosed as other muscle diseases. sIBM remains refractory to treatment (e.g., glucocorticoid, and immunosuppressive/immunomodulatory/immunobiological drugs). Although there have been no robust clinical trials, training exercise/physiotherapy should be prescribed regularly in sIBM patients.


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    -  de Souza FH
    -  Behrens Pinto GL
    -  de Souza JM
    -  Olivo Pallo PA
    -  Hoff LS
    -  Shinjo SK
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