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Kimura disease: A rare presentation in the rheumatology clinic

1 Department of Internal Medicine, Command Hospital, (SC), Pune, Maharashtra, India
2 Department of Rheumatology, Command Hospital, (SC), Pune, Maharashtra, India
3 Department of Otorhinolaryngology, Command Hospital, (SC), Pune, Maharashtra, India
4 Department of Pathology, Command Hospital, (SC), Pune, Maharashtra, India
5 Department of Radiology, Armed Forces Medical College, Pune, Maharashtra, India

Correspondence Address:
Arun Hegde,
Department of Rheumatology, Command Hospital, (SC), Pune - 410040, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/injr.injr_132_20

Kimura disease (KD) is a rare chronic inflammatory disorder of unknown cause, primarily seen in young Asian males. The disease is characterized by painless subcutaneous swelling in head and neck region, accompanied by regional lymphadenopathy and frequent salivary gland enlargement. Blood and tissue eosinophilia, and elevated immunoglobulin E (IgE) levels, are common associations. Characteristic histopathological findings of biopsy specimens obtained from the subcutaneous swellings or lymph nodes include eosinophilic infiltrates, follicular hyperplasia, and proliferation of postcapillary venules. The course is usually waxing and waning, albeit benign. Early diagnosis may spare the patient from unnecessary invasive procedures. We herein, describe a case of KD in an 18 years old male, who presented with subcutaneous swelling in the both cheek (right more than left) in 2014, underwent multiple surgical interventions for the same, before being reassessed and finally diagnosed as KD in 2020, based upon peripheral blood eosinophilia, raised serum IgE levels and histopathological findings. He subsequently made a good recovery on oral steroids.

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