Indian Journal of Rheumatology

REVIEW ARTICLE
Year
: 2017  |  Volume : 12  |  Issue : 4  |  Page : 219--222

Vitamin D and autoimmune diseases


Shir Azrielant1, Yehuda Shoenfeld2 
1 Sheba Medical Center, The Zabludowicz Center for Autoimmune Diseases, Tel-Hashomer, Ramat-Gan; Sackler Faculty of Medicine, Tel-Aviv University, Israel
2 Sheba Medical Center, The Zabludowicz Center for Autoimmune Diseases, Tel-Hashomer, Ramat-Gan; Sackler Faculty of Medicine, Tel-Aviv University; Tel-Aviv University, Incumbent of the Laura Schwarz-Kip Chair for Research of Autoimmune Diseases, Ramat-Aviv, Tel-Aviv, Israel

Correspondence Address:
Yehuda Shoenfeld
Sheba Medical Center, Zabludowicz Center for Autoimmune Diseases, Tel-Hashomer 5265601
Israel

Vitamin D and its deficiency are becoming a subject of great interest in recent years. In addition to the well-known role of vitamin D in maintaining bone health, evidence from recent years are accumulating in favor of its importance in the functioning of the immune system. The association between vitamin D deficiency and autoimmune diseases has been supported by epidemiological studies, demonstrating higher prevalence of vitamin D deficiency among autoimmune patients, in comparison to the general population. Vitamin D was also associated to various autoimmune diseases in both molecular and interventional studies; among the associated diseases are: systemic lupus erythematosus, type 1 diabetes mellitus, multiple sclerosis and others. In this review, relevant literature on the association between autoimmunity and vitamin D deficiency will be reviewed and discussed, as well as a summary of important recommendations for vitamin D supplementations in autoimmune patients.


How to cite this article:
Azrielant S, Shoenfeld Y. Vitamin D and autoimmune diseases.Indian J Rheumatol 2017;12:219-222


How to cite this URL:
Azrielant S, Shoenfeld Y. Vitamin D and autoimmune diseases. Indian J Rheumatol [serial online] 2017 [cited 2021 Sep 28 ];12:219-222
Available from: https://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=4;spage=219;epage=222;aulast=Azrielant;type=0