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  Indian J Med Microbiol
 

Figure 1: Asymptomatic low-grade myopathy in overlap syndrome with anti-Ku antibodies. A 67-year-old female developed inflammatory arthritis, Raynaud's phenomenon, and diffuse skin thickening (modified Rodnan Skin Score 18/51) with positive Anti-Ku antibodies. There were no myopathic symptoms/signs, but moderately elevated creatine kinase was identified on routine biochemistry. The arthritis was treated with steroids (a) with mycophenolate mofetil added as a steroid-sparing agent (b), leading to reduction in CpK to normal range. Asymptomatic nonspecific interstitial pneumonia was present on computed tomography thorax

Figure 1: Asymptomatic low-grade myopathy in overlap syndrome with anti-Ku antibodies. A 67-year-old female developed inflammatory arthritis, Raynaud's phenomenon, and diffuse skin thickening (modified Rodnan Skin Score 18/51) with positive Anti-Ku antibodies. There were no myopathic symptoms/signs, but moderately elevated creatine kinase was identified on routine biochemistry. The arthritis was treated with steroids (a) with mycophenolate mofetil added as a steroid-sparing agent (b), leading to reduction in CpK to normal range. Asymptomatic nonspecific interstitial pneumonia was present on computed tomography thorax