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  Indian J Med Microbiol
 

Figure 4: The clinicoserological spectrum of overlap connective tissue disease. The square boxes reflect the clinical diagnosis, with the oval shapes representing the common clinical characteristics (and relative frequency) of relevant antibody specificities. For example, anti-Ku antibodies, meanwhile, can be found in systemic sclerosis, systemic lupus erythematosus, overlap systemic lupus erythematosus/myositis, or overlap systemic sclerosis/myositis. The mixed connective tissue disease is frequently diagnosed in all patients with anti-U1 RNP antibodies, although only a minority of patients with this antibody will truly have overlap features of systemic lupus erythematosus, systemic sclerosis, and myositis

Figure 4: The clinicoserological spectrum of overlap connective tissue disease. The square boxes reflect the clinical diagnosis, with the oval shapes representing the common clinical characteristics (and relative frequency) of relevant antibody specificities. For example, anti-Ku antibodies, meanwhile, can be found in systemic sclerosis, systemic lupus erythematosus, overlap systemic lupus erythematosus/myositis, or overlap systemic sclerosis/myositis. The mixed connective tissue disease is frequently diagnosed in all patients with anti-U1 RNP antibodies, although only a minority of patients with this antibody will truly have overlap features of systemic lupus erythematosus, systemic sclerosis, and myositis